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Loss of Ypk1, the Yeast Homolog to the Human Serum- and Glucocorticoid-induced Protein Kinase, Accelerates Phospholipase B1-mediated Phosphatidylcholine Deacylation

Ypk1, the yeast homolog of the human serum- and glucocorticoid-induced kinase (Sgk1), affects diverse cellular activities, including sphingolipid homeostasis. We now report that Ypk1 also impacts the turnover of the major phospholipid, phosphatidylcholine (PC). Pulse-chase radiolabeling reveals that...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Surlow, Beth A., Cooley, Benjamin M., Needham, Patrick G., Brodsky, Jeffrey L., Patton-Vogt, Jana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223355/
https://ncbi.nlm.nih.gov/pubmed/25258318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581157
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