Nerve Growth Factor (NGF) Regulates Activity of Nuclear Factor of Activated T-cells (NFAT) in Neurons via the Phosphatidylinositol 3-Kinase (PI3K)-Akt-Glycogen Synthase Kinase 3β (GSK3β) Pathway

The Ca(2+)/calcineurin-dependent transcription factor nuclear factor of activated T-cells (NFAT) plays an important role in regulating many neuronal functions, including excitability, axonal growth, synaptogenesis, and neuronal survival. NFAT can be activated by action potential firing or depolariza...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Kim, Man-Su, Shutov, Leonid P., Gnanasekaran, Aswini, Lin, Zhihong, Rysted, Jacob E., Ulrich, Jason D., Usachev, Yuriy M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Neurobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223335/
https://ncbi.nlm.nih.gov/pubmed/25231981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587188
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