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Reconstitution of Actin-based Motility by Vasodilator-stimulated Phosphoprotein (VASP) Depends on the Recruitment of F-actin Seeds from the Solution Produced by Cofilin

Vasodilator-stimulated phosphoprotein (VASP) is active in many filopodium-based and cytoskeleton reorganization processes. It is not fully understood how VASP directly functions in actin-based motility and how regulatory proteins affect its function. Here, we combine bead motility assay and single f...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Siton, Orit, Bernheim-Groswasser, Anne
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223328/
https://ncbi.nlm.nih.gov/pubmed/25246528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586958
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