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Silencing by H-NS Potentiated the Evolution of Salmonella

The bacterial H-NS protein silences expression from sequences with higher AT-content than the host genome and is believed to buffer the fitness consequences associated with foreign gene acquisition. Loss of H-NS results in severe growth defects in Salmonella, but the underlying reasons were unclear....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ali, Sabrina S., Soo, Jeremy, Rao, Chitong, Leung, Andrea S., Ngai, David Hon-Man, Ensminger, Alexander W., Navarre, William Wiley
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223078/
https://ncbi.nlm.nih.gov/pubmed/25375226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004500
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