Multiple Functional Risk Variants in a SMAD7 Enhancer Implicate a Colorectal Cancer Risk Haplotype

Genome-wide association studies (GWAS) of colorectal cancer (CRC) have led to the identification of a number of common variants associated with modest risk. Several risk variants map within the vicinity of TGFβ/BMP signaling pathway genes, including rs4939827 within an intron of SMAD7 at 18q21.1. A...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Fortini, Barbara K., Tring, Stephanie, Plummer, Sarah J., Edlund, Christopher K., Moreno, Victor, Bresalier, Robert S., Barry, Elizabeth L., Church, Timothy R., Figueiredo, Jane C., Casey, Graham
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223076/
https://ncbi.nlm.nih.gov/pubmed/25375357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111914
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