Co-dependence of HTLV-1 p12 and p8 Functions in Virus Persistence

HTLV-1 orf-I is linked to immune evasion, viral replication and persistence. Examining the orf-I sequence of 160 HTLV-1-infected individuals; we found polymorphism of orf-I that alters the relative amounts of p12 and its cleavage product p8. Three groups were identified on the basis of p12 and p8 ex...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Pise-Masison, Cynthia A., de Castro-Amarante, Maria Fernanda, Enose-Akahata, Yoshimi, Buchmann, R. Cody, Fenizia, Claudio, Washington Parks, Robyn, Edwards, Dustin, Fiocchi, Martina, Alcantara, Luiz Carlos, Bialuk, Izabela, Graham, Jhanelle, Walser, Jean-Claude, McKinnon, Katherine, Galvão-Castro, Bernardo, Gessain, Antoine, Venzon, David, Jacobson, Steven, Franchini, Genoveffa
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223054/
https://ncbi.nlm.nih.gov/pubmed/25375128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004454
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