NMR-Based Detection of Hydrogen/Deuterium Exchange in Liposome-Embedded Membrane Proteins

Membrane proteins play key roles in biology. Determination of their structure in a membrane environment, however, is highly challenging. To address this challenge, we developed an approach that couples hydrogen/deuterium exchange of membrane proteins to rapid unfolding and detection by solution-stat...

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Vydáno v:PLoS One
Hlavní autoři: Yao, Xuejun, Dürr, Ulrich H. N., Gattin, Zrinka, Laukat, Yvonne, Narayanan, Rhagavendran L., Brückner, Ann-Kathrin, Meisinger, Chris, Lange, Adam, Becker, Stefan, Zweckstetter, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223039/
https://ncbi.nlm.nih.gov/pubmed/25375235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112374
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