Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin

UbcH10 is a component of the Ubiquitin Conjugation Enzymes (Ubc; E2) involved in the ubiquitination cascade controlling the cell cycle progression, whereby ubiquitin, activated by E1, is transferred through E2 to the target protein with the involvement of E3 enzymes. In this work we propose the firs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Correale, Stefania, de Paola, Ivan, Morgillo, Carmine Marco, Federico, Antonella, Zaccaro, Laura, Pallante, Pierlorenzo, Galeone, Aldo, Fusco, Alfredo, Pedone, Emilia, Luque, F. Javier, Catalanotti, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223017/
https://ncbi.nlm.nih.gov/pubmed/25375166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112082
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