Analysis of Nuclear Export Sequence Regions of FUS-Related RNA-Binding Proteins in Essential Tremor

BACKGROUND AND OBJECTIVE: Genes encoding RNA-binding proteins, including FUS and TDP43, play a central role in different neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Recently, a mutation located in the nuclear export signal (NES) of the FUS...

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Publicado en:PLoS One
Autores principales: Lorenzo-Betancor, Oswaldo, Ogaki, Kotaro, Soto-Ortolaza, Alexandra, Labbé, Catherine, Vilariño-Güell, Carles, Rajput, Alex, Rajput, Ali H., Pastor, Pau, Ortega, Sara, Lorenzo, Elena, Strongosky, Audrey J., van Gerpen, Jay A., Uitti, Ryan J., Wszolek, Zbigniew K., Ross, Owen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222957/
https://ncbi.nlm.nih.gov/pubmed/25375143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111989
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