Menthol Inhibits Detrusor Contractility Independently of TRPM8 Activation

Agonists such as icilin and menthol can activate the cool temperature-sensitive ion channel TRPM8. However, biological responses to menthol may occur independently of TRPM8 activation. In the rodent urinary bladder, menthol facilitates the micturition reflex but inhibits muscarinic contractions of t...

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Vydáno v:PLoS One
Hlavní autoři: Ramos-Filho, Antonio Celso Saragossa, Shah, Ajay, Augusto, Taize Machado, Barbosa, Guilherme Oliveira, Leiria, Luiz Osorio, de Carvalho, Hernandes Faustino, Antunes, Edson, Grant, Andrew Douglas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222941/
https://ncbi.nlm.nih.gov/pubmed/25375115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111616
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