Two novel mutations of pfdhps K540T and I588F, affecting sulphadoxine-pyrimethamine-resistant response in uncomplicated falciparum malaria at Banjar district, South Kalimantan Province, Indonesia

BACKGROUND: Mutations in pfdhfr and pfdhps genes have been shown to associate with sulphadoxine-pyrimethamine (SP) resistance of Plasmodium falciparum parasites. However, pfdhfr, pfdhps genotypes and the correlations to SP treatment outcome in Indonesia has not yet been well analysed. METHODS: After...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Basuki, Sukmawati, Fitriah, Riyanto, Sugeng, Budiono, Dachlan, Yoes P, Uemura, Haruki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222776/
https://ncbi.nlm.nih.gov/pubmed/25187019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-135
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