24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These rhythms are paralleled by 24-hour rhythms of large portions of the transcriptome. The role of dynamic DNA methylation in influencing these rhyt...

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Publicat a:PLoS Genet
Autors principals: Lim, Andrew S. P., Srivastava, Gyan P., Yu, Lei, Chibnik, Lori B., Xu, Jishu, Buchman, Aron S., Schneider, Julie A., Myers, Amanda J., Bennett, David A., De Jager, Philip L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222754/
https://ncbi.nlm.nih.gov/pubmed/25375876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004792
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