24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex

Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These rhythms are paralleled by 24-hour rhythms of large portions of the transcriptome. The role of dynamic DNA methylation in influencing these rhyt...

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Pubblicato in:PLoS Genet
Autori principali: Lim, Andrew S. P., Srivastava, Gyan P., Yu, Lei, Chibnik, Lori B., Xu, Jishu, Buchman, Aron S., Schneider, Julie A., Myers, Amanda J., Bennett, David A., De Jager, Philip L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222754/
https://ncbi.nlm.nih.gov/pubmed/25375876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004792
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