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Nucleotide signalling during inflammation

Inflammatory conditions are associated with the extracellular release of nucleotides, particularly ATP. In the extracellular compartment, ATP predominantly functions as a signalling molecule through the activation of purinergic P2 receptors. Metabotropic P2Y receptors are G-protein-coupled, whereas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Idzko, Marco, Ferrari, Davide, Eltzschig, Holger K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222675/
https://ncbi.nlm.nih.gov/pubmed/24828189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13085
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