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Clinicopathological significance and potential drug target of p15(INK4B) in multiple myeloma
Multiple myeloma (MM) is a clonal malignancy characterized by the proliferation of malignant plasma cells in the bone marrow and the production of monoclonal immunoglobulin. In addition to genetic changes, gene hypermethylation is an alternative mechanism of tumor suppressor gene inactivation in MM....
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Publicado no: | Drug Des Devel Ther |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222634/ https://ncbi.nlm.nih.gov/pubmed/25382971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71088 |
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