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Clinicopathological significance and potential drug target of p15(INK4B) in multiple myeloma

Multiple myeloma (MM) is a clonal malignancy characterized by the proliferation of malignant plasma cells in the bone marrow and the production of monoclonal immunoglobulin. In addition to genetic changes, gene hypermethylation is an alternative mechanism of tumor suppressor gene inactivation in MM....

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Li, Jun, Bi, Lintao, Lin, Yumei, Lu, Zhenxia, Hou, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222634/
https://ncbi.nlm.nih.gov/pubmed/25382971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71088
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