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Systematic Analysis of the Role of RNA-Binding Proteins in the Regulation of RNA Stability

mRNA half-lives are transcript-specific and vary over a range of more than 100-fold in eukaryotic cells. mRNA stabilities can be regulated by sequence-specific RNA-binding proteins (RBPs), which bind to regulatory sequence elements and modulate the interaction of the mRNA with the cellular RNA degra...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Hasan, Ayesha, Cotobal, Cristina, Duncan, Caia D. S., Mata, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222612/
https://ncbi.nlm.nih.gov/pubmed/25375137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004684
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