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Challenges in diagnostic accuracy studies in primary care: the fecal calprotectin example

BACKGROUND: Low disease prevalence and lack of uniform reference standards in primary care induce methodological challenges for investigating the diagnostic accuracy of a test. We present a study design that copes with these methodological challenges and discuss the methodological implications of ou...

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Publicat a:BMC Fam Pract
Autors principals: Holtman, Gea A, Leeuwen, Yvonne Lisman-van, Kollen, Boudewijn J, Escher, Johanna C, Kindermann, Angelika, Rheenen, Patrick F van, Berger, Marjolein Y
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222604/
https://ncbi.nlm.nih.gov/pubmed/24274463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2296-14-179
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