Synthesis and immunological evaluation of protein conjugates of Neisseria meningitidis X capsular polysaccharide fragments

A vaccine to prevent infections from the emerging Neisseria meningitidis X (MenX) is becoming an urgent issue. Recently MenX capsular polysaccharide (CPS) fragments conjugated to CRM(197) as carrier protein have been confirmed at preclinical stage as promising candidates for vaccine development. How...

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Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Morelli, Laura, Cancogni, Damiano, Tontini, Marta, Nilo, Alberto, Filippini, Sara, Costantino, Paolo, Romano, Maria Rosaria, Berti, Francesco, Adamo, Roberto, Lay, Luigi
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222376/
https://ncbi.nlm.nih.gov/pubmed/25383107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.247
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