Ca(2+) release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor

Although several cancer immunotherapy strategies are currently based on the use of analog peptides and on the modulation of the TCR affinity of adoptively transferred T cells, it remains unclear whether tumor specific T cell activation by strong and weak TCR stimuli evoke different Ca(2+) signatures...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Chen, Ji-Li, Morgan, Anthony J., Stewart-Jones, Guillaume, Shepherd, Dawn, Bossi, Giovanna, Wooldridge, Linda, Hutchinson, Sarah L., Sewell, Andrew K., Griffiths, Gillian M., van der Merwe, P. Anton, Jones, E. Yvonne, Galione, Antony, Cerundolo, Vincenzo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222200/
https://ncbi.nlm.nih.gov/pubmed/20053942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902103
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