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Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy

INTRODUCTION: Patients with febrile neutropenia (FN) exhibit changes in extracellular fluid that may alter the plasma concentrations of beta-lactams and result in therapeutic failure or toxicity. We evaluated the pharmacokinetics of piperacillin/tazobactam in patients with hematological malignancies...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Álvarez, José C, Cuervo, Sonia I, Garzón, Javier R, Gómez, Julio C, Díaz, Jorge Augusto, Silva, Edelberto, Sánchez, Ricardo, Cortés, Jorge A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222139/
https://ncbi.nlm.nih.gov/pubmed/24286231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-59
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