A systems biology analysis of the changes in gene expression via silencing of HPV-18 E1 expression in HeLa cells

Previous studies have reported the detection of a truncated E1 mRNA generated from HPV-18 in HeLa cells. Although it is unclear whether a truncated E1 protein could function as a replicative helicase for viral replication, it would still retain binding sites for potential interactions with different...

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Bibliographic Details
Published in:Open Biol
Main Authors: Castillo, Andres, Wang, Lu, Koriyama, Chihaya, Eizuru, Yoshito, Jordan, King, Akiba, Suminori
Format: Artigo
Language:Inglês
Published: The Royal Society 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221889/
https://ncbi.nlm.nih.gov/pubmed/25297386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130119
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