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Chronic intermittent hypoxia–hypercapnia blunts heart rate responses and alters neurotransmission to cardiac vagal neurons

Patients with obstructive sleep apnoea experience chronic intermittent hypoxia–hypercapnia (CIHH) during sleep that elicit sympathetic overactivity and diminished parasympathetic activity to the heart, leading to hypertension and depressed baroreflex sensitivity. The parasympathetic control of heart...

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Publicado en:J Physiol
Autores principales: Dyavanapalli, Jhansi, Jameson, Heather, Dergacheva, Olga, Jain, Vivek, Alhusayyen, Mona, Mendelowitz, David
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221821/
https://ncbi.nlm.nih.gov/pubmed/24835174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.273482
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