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Transient impairment of the axolemma following regional anaesthesia by lidocaine in humans

The local anaesthetic lidocaine is known to block voltage-gated Na(+) channels (VGSCs), although at high concentration it was also reported to block other ion channel currents as well as to alter lipid membranes. The aim of this study was to investigate whether the clinical regional anaesthetic acti...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Moldovan, Mihai, Lange, Kai Henrik Wiborg, Aachmann-Andersen, Niels Jacob, Kjær, Troels Wesenberg, Olsen, Niels Vidiendal, Krarup, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221817/
https://ncbi.nlm.nih.gov/pubmed/24710060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.270827
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