Lentivector Integration Sites in Ependymal Cells From a Model of Metachromatic Leukodystrophy: Non-B DNA as a New Factor Influencing Integration

The blood–brain barrier controls the passage of molecules from the blood into the central nervous system (CNS) and is a major challenge for treatment of neurological diseases. Metachromatic leukodystrophy is a neurodegenerative lysosomal storage disease caused by loss of arylsulfatase A (ARSA) activ...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: McAllister, Robert G, Liu, Jiahui, Woods, Matthew W, Tom, Sean K, Rupar, C Anthony, Barr, Stephen D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221599/
https://ncbi.nlm.nih.gov/pubmed/25158091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.39
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