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Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis
Talins are adaptor proteins that regulate focal adhesion signaling by conjugating integrins to the cytoskeleton. Talins directly bind integrins and are essential for integrin activation. We previously showed that β1 integrins are activated in metastatic prostate cancer (PCa) cells, increasing PCa me...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4221586/ https://ncbi.nlm.nih.gov/pubmed/24793790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.116 |
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