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Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress and brain injury in mice with ischemic stroke and bone fracture

Bone fracture at the acute stage of stroke exacerbates stroke injury by increasing neuroinflammation. We hypothesize that activation of α-7 nicotinic acetylcholine (α-7 nAchR) agonist attenuates neuroinflammation and oxidative stress, and reduces brain injury in mice with bone fracture and stroke. P...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Han, Zhenying, Li, Li, Wang, Liang, Degos, Vincent, Maze, Mervyn, Su, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221541/
https://ncbi.nlm.nih.gov/pubmed/25040630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12817
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