Brain Tumor Cells in Circulation are Enriched for Mesenchymal Gene Expression

Glioblastoma (GBM) is a highly aggressive brain cancer characterized by local invasion and angiogenic recruitment, yet metastatic dissemination is extremely rare. Here, we adapted a microfluidic device to deplete hematopoietic cells from blood specimens of patients with GBM, uncovering evidence of c...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancer Discov
Κύριοι συγγραφείς: Sullivan, James P., Nahed, Brian V., Madden, Marissa W., Oliveira, Samantha M., Springer, Simeon, Bhere, Deepak, Chi, Andrew S., Wakimoto, Hiroaki, Rothenberg, S. Michael, Sequist, Lecia V., Kapur, Ravi, Shah, Khalid, Iafrate, A. John, Curry, William T., Loeffler, Jay S., Batchelor, Tracy T., Louis, David N., Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221467/
https://ncbi.nlm.nih.gov/pubmed/25139148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0471
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