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Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines

This study investigated the effects on the tumor microenvironment of combining antiangiogenic tyrosine kinase inhibitors (TKI) with therapeutic vaccines, and in particular, how vascular changes affect tumor-infiltrating immune cells. We conducted studies using a TKI (sunitinib or sorafenib) in combi...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Res
Main Authors: Farsaci, Benedetto, Donahue, Renee N., Coplin, Michael A., Grenga, Italia, Lepone, Lauren M., Molinolo, Alfredo A., Hodge, James W.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221465/
https://ncbi.nlm.nih.gov/pubmed/25092771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0076
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