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IL4 Limits the Efficacy of Tumor-Targeted Antibody Therapy in a Murine Model

Tumor-targeted antibody therapy has had a major impact on reducing morbidity and mortality in a wide range of cancers. Antibodies mediate their antitumor activity in part by activating immune effector cells; however, the tumor microenvironment (TME) is enriched with cellular and soluble mediators th...

詳細記述

保存先:
書誌詳細
出版年:Cancer Immunol Res
主要な著者: Surana, Rishi, Wang, Shangzi, Xu, Wei, Jablonski, Sandra A., Weiner, Louis M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221424/
https://ncbi.nlm.nih.gov/pubmed/25204776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0103
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