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IL4 Limits the Efficacy of Tumor-Targeted Antibody Therapy in a Murine Model
Tumor-targeted antibody therapy has had a major impact on reducing morbidity and mortality in a wide range of cancers. Antibodies mediate their antitumor activity in part by activating immune effector cells; however, the tumor microenvironment (TME) is enriched with cellular and soluble mediators th...
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Wydane w: | Cancer Immunol Res |
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Główni autorzy: | , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
2014
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4221424/ https://ncbi.nlm.nih.gov/pubmed/25204776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0103 |
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