S-1 as Monotherapy or in Combination With Leucovorin as Second-Line Treatment in Gemcitabine-Refractory Advanced Pancreatic Cancer: A Randomized, Open-Label, Multicenter, Phase II Study

BACKGROUND. In this study, we compared the efficacy and safety of the oral fluoropyrimidine S-1 as monotherapy or in combination with leucovorin as the second-line treatment for patients with metastatic pancreatic cancer whose disease had progressed on gemcitabine treatment. METHODS. The study was a...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Ge, Feijiao, Xu, Nong, Bai, Yuxian, Ba, Yi, Zhang, Yanqiao, Li, Fei, Xu, Huayan, Jia, Ru, Wang, Yan, Lin, Li, Xu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Clinical Trial Results
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221373/
https://ncbi.nlm.nih.gov/pubmed/25273077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0223
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