A Prospective Study of Shortened Vitamin Supplementation Prior to Cisplatin–Pemetrexed Therapy for Non-Small Cell Lung Cancer

BACKGROUND. Prior supplementation with folic acid and vitamin B(12) is required to reduce pemetrexed therapy toxicity; the recommended lead-in time is at least 7 days. On the basis of previous pharmacokinetic and clinical studies, we hypothesized that the lead-in time could be shortened to 24 hours,...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Takagi, Yusuke, Hosomi, Yukio, Sunami, Kuniko, Nakahara, Yoshiro, Okuma, Yusuke, Yomota, Makiko, Shimokawa, Tsuneo, Nagamata, Makoto, Iguchi, Mari, Okamoto, Hiroaki, Okamura, Tatsuru, Shibuya, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Symptom Management and Supportive Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221372/
https://ncbi.nlm.nih.gov/pubmed/25260366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0221
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