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Isolation and phenotypic characterization of virulence-deficient mutants of Vibrio cholerae.

Mutants of Vibrio cholerae was isolated on the basis of reduced ability to induce diarrhea in orally challenged infant mice. Nitrosoguanidine-treated clones were screened for low fluid accumulation ratios in individual mice, and presumptive mutants were confirmed in additional mouse tests. Mutants w...

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Detalhes bibliográficos
Main Authors: Baselski, V S, Upchurch, S, Parker, C D
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC422134/
https://ncbi.nlm.nih.gov/pubmed/730346
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