A prospective, randomized, placebo-controlled, double-blind, multicenter study of the effects of irbesartan on aortic dilatation in Marfan syndrome (AIMS trial): study protocol

BACKGROUND: Cardiovascular complications are the leading cause of mortality and morbidity in Marfan syndrome (MFS), a dominantly inherited disorder caused by mutations in the gene that encodes fibrillin-1. There are approximately 18,000 patients in the UK with MFS. Current treatment includes careful...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Mullen, Michael J, Flather, Marcus D, Jin, Xu Yu, Newman, William G, Erdem, Guliz, Gaze, David, Valencia, Oswaldo, Banya, Winston, Foley, Claire E, Child, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220813/
https://ncbi.nlm.nih.gov/pubmed/24289736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-14-408
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