Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma

Most follicular lymphomas (FLs) are genetically defined by the t(14;18)(q32;q21) translocation that juxtaposes the BCL2 gene to the immunoglobulin heavy chain (IgH) 3' regulatory regions (IgH-3'RRs). Despite this recurrent translocation, FL cases are heterogeneous in terms of intratumoral...

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Vydáno v:Blood Cancer J
Hlavní autoři: Barreca, A, Martinengo, C, Annaratone, L, Righi, L, Chiappella, A, Ladetto, M, Demurtas, A, Chiusa, L, Stacchini, A, Crosetto, N, van Oudenaarden, A, Chiarle, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220646/
https://ncbi.nlm.nih.gov/pubmed/25303368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2014.67
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