Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trials

INTRODUCTION: Small increases in mean serum creatinine (SCr) were observed in studies of rheumatoid arthritis patients during tofacitinib treatment. These SCr changes were investigated and potential mechanisms explored. METHODS: SCr values and renal adverse event data were pooled from five Phase 3 a...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Isaacs, John D, Zuckerman, Andrea, Krishnaswami, Sriram, Nduaka, Chudy, Lan, Shuping, Hutmacher, Matthew M, Boy, Mary G, Kowalski, Ken, Menon, Sujatha, Riese, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220634/
https://ncbi.nlm.nih.gov/pubmed/25063045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4673
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