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Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients
Here, we demonstrate that electroporation-enhanced immunization with a rationally designed HPV DNA vaccine (GX-188E), preferentially targeting HPV antigens to dendritic cells, elicits a significant E6/E7-specific IFN-γ-producing T-cell response in all nine cervical intraepithelial neoplasia 3 (CIN3)...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Pub. Group
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220493/ https://ncbi.nlm.nih.gov/pubmed/25354725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6317 |
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