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A new role for Hedgehogs in juxtacrine signaling
The Hedgehog pathway plays important roles in embryonic development, adult stem cell maintenance and tumorigenesis. In mammals these effects are mediated by Sonic, Desert and Indian Hedgehog (Shh, Dhh and Ihh). Shh undergoes autocatalytic cleavage and dual lipidation prior to secretion and forming a...
Gardado en:
| Publicado en: | Mech Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220416/ https://ncbi.nlm.nih.gov/pubmed/24342078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2013.12.002 |
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