Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

Heart tissue destruction in chronic Chagas disease cardiopathy (CCC) may be caused by autoimmune recognition of heart tissue by a mononuclear cell infiltrate decades after Trypanosoma cruzi infection. Indirect evidence suggests that there is antigenic crossreactivity between T. cruzi and heart tissu...

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Main Authors: Cunha-Neto, E, Duranti, M, Gruber, A, Zingales, B, De Messias, I, Stolf, N, Bellotti, G, Patarroyo, M E, Pilleggi, F, Kalil, J
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42203/
https://ncbi.nlm.nih.gov/pubmed/7536937
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