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Expanding the functional role of long noncoding RNAs

New findings bring to light a previously unappreciated mechanism involved in the regulation of the oncoprotein MYC. Interesting observations find that the long noncoding RNA (lncRNA) PVT1 is active in controlling levels of MYC through regulation of MYC protein stability.

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Johnsson, Per, Morris, Kevin V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220152/
https://ncbi.nlm.nih.gov/pubmed/25104732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.104
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