Detecting “different”: Pyrin senses modified GTPases

Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.

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Bibliographic Details
Published in:Cell Res
Main Authors: de Zoete, Marcel R, Flavell, Richard A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Research Highlight
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220150/
https://ncbi.nlm.nih.gov/pubmed/25091449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.101
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