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Ryanodine receptor 2 contributes to hemorrhagic shock-induced bi-phasic vascular reactivity in rats

AIM: Ryanodine receptor 2 (RyR2) is a critical component of intracellular Ca(2+) signaling in vascular smooth muscle cells (VSMCs). The aim of this study was to investigate the role of RyR2 in abnormal vascular reactivity after hemorrhagic shock in rats. METHODS: SD rats were hemorrhaged and maintai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Zhou, Rong, Ding, Xiao-li, Liu, Liang-ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220076/
https://ncbi.nlm.nih.gov/pubmed/25263335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.83
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