Epigenetic Modification Agents Improve Genomic Methylation Reprogramming in Porcine Cloned Embryos

Incomplete DNA methylation reprogramming in cloned embryos leads to low cloning efficiency. Our previous studies showed that the epigenetic modification agents 5-aza-2’-deoxycytidine (5-aza-dC) or trichostatin A (TSA) could enhance the developmental competence of porcine cloned embryos. Here, we inv...

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Vydáno v:J Reprod Dev
Hlavní autoři: HUAN, Yan Jun, ZHU, Jiang, WANG, Hong Mei, WU, Zhan Feng, ZHANG, Ji Guang, XIE, Bing Teng, LI, Jing Yu, KONG, Qing Ran, LIU, Zhong Hua, HE, Hong Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Society for Reproduction and Development 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219995/
https://ncbi.nlm.nih.gov/pubmed/25047549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2014-062
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