Epigenetic Modification Agents Improve Genomic Methylation Reprogramming in Porcine Cloned Embryos

Incomplete DNA methylation reprogramming in cloned embryos leads to low cloning efficiency. Our previous studies showed that the epigenetic modification agents 5-aza-2’-deoxycytidine (5-aza-dC) or trichostatin A (TSA) could enhance the developmental competence of porcine cloned embryos. Here, we inv...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: HUAN, Yan Jun, ZHU, Jiang, WANG, Hong Mei, WU, Zhan Feng, ZHANG, Ji Guang, XIE, Bing Teng, LI, Jing Yu, KONG, Qing Ran, LIU, Zhong Hua, HE, Hong Bin
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219995/
https://ncbi.nlm.nih.gov/pubmed/25047549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2014-062
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