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A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1(+) that encoded for an essential P-type proton ATPase. An Asp-138 to Asn mutation resulted in reduced Pma1 activity, concomitant with an increase in the chronological lifespan of this fissio...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Naito, Chikako, Ito, Hirokazu, Oshiro, Tomoko, Ohtsuka, Hokuto, Murakami, Hiroshi, Aiba, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219986/
https://ncbi.nlm.nih.gov/pubmed/25379379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.09.006
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