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Synthesis of an Aminooxy Derivative of the Trisaccharide Globotriose Gb3

The synthesis of α-aminooxy trisaccharide moiety [α-d-Gal-(1,4)-β-d-Gal-(1,4)-β-d-Glc-α-aminooxy], related to the cell surface globotriaosylceramide (Gb3) receptor of the B subunit of the AB(5) Shiga toxin of Shigella dysenteriae, has been synthesized for the first time in 11 steps with a 15% overal...

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Bibliographic Details
Published in:J Carbohydr Chem
Main Authors: Ghosh, Samir, Andreana, Peter R.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219983/
https://ncbi.nlm.nih.gov/pubmed/25382930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328303.2014.925913
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