Maximizing T(2)-exchange in Dy(3+)DOTA-(amide)(X) chelates: Fine-tuning the water molecule exchange rate for enhanced T(2) contrast in MRI

PURPOSE: The water molecule exchange rates in a series of DyDOTA-(amide)(X) chelates were fine-tuned to maximize the effects of T(2)-exchange line broadening and improve T(2) contrast. METHODS: Four DyDOTA-(amide)(X) chelates having a variable number of glycinate side-arms were prepared and characte...

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Detalhes bibliográficos
Publicado no:Magn Reson Med
Main Authors: Soesbe, Todd C., Ratnakar, S. James, Milne, Mark, Zhang, Shanrong, Do, Quyen N., Kovacs, Zoltan, Sherry, A. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219925/
https://ncbi.nlm.nih.gov/pubmed/24390729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25091
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