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Regulation of RAB5C Is Important for the Growth Inhibitory Effects of MiR-509 in Human Precursor-B Acute Lymphoblastic Leukemia

MicroRNAs (miRs) regulate essentially all cellular processes, but few miRs are known to inhibit growth of precursor-B acute lymphoblastic leukemias (B-ALLs). We identified miR-509 via a human genome-wide gain-of-function screen for miRs that inhibit growth of the NALM6 human B-ALL cell line. MiR-509...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tan, Yee Sun, Kim, MinJung, Kingsbury, Tami J., Civin, Curt I., Cheng, Wen-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219775/
https://ncbi.nlm.nih.gov/pubmed/25368993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111777
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