How Difficult Is Inference of Mammalian Causal Gene Regulatory Networks?

Gene regulatory networks (GRNs) play a central role in systems biology, especially in the study of mammalian organ development. One key question remains largely unanswered: Is it possible to infer mammalian causal GRNs using observable gene co-expression patterns alone? We assembled two mouse GRN da...

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Veröffentlicht in:PLoS One
Hauptverfasser: Djordjevic, Djordje, Yang, Andrian, Zadoorian, Armella, Rungrugeecharoen, Kevin, Ho, Joshua W. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219746/
https://ncbi.nlm.nih.gov/pubmed/25369032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111661
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