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CARD14 Expression in Dermal Endothelial Cells in Psoriasis

Mutations in the caspase recruitment domain, family member 14 (CARD14) gene have recently been described in psoriasis patients, and explain the psoriasis susceptibility locus 2 (PSORS2). CARD14 is a scaffolding protein that regulates NF-κB activation, and psoriasis-associated CARD14 mutations lead t...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Harden, Jamie L., Lewis, Steven M., Pierson, Katherine C., Suárez-Fariñas, Mayte, Lentini, Tim, Ortenzio, Francesca S., Zaba, Lisa C., Goldbach-Mansky, Raphaela, Bowcock, Anne M., Lowes, Michelle A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219711/
https://ncbi.nlm.nih.gov/pubmed/25369198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111255
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