No Difference in the Rate of Change in Telomere Length or Telomerase Activity in HIV-Infected Patients after Three Years of Darunavir/Ritonavir with and without Nucleoside Analogues in the MONET Trial

OBJECTIVE: To determine whether nucleos(t)ide reverse transcriptase inhibitors (NRTI) contribute to an accelerated loss in telomere length (TL) in HIV-infected patients on antiretroviral therapy (ART). DESIGN: Substudy of randomised controlled trial. METHODS: Patients with HIV RNA <50 copies/mL o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Solomon, Ajantha, Tennakoon, Surekha, Leeansyah, Edwin, Arribas, Jose, Hill, Andrew, Van Delft, Yvon, Moecklinghoff, Christiane, Lewin, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219673/
https://ncbi.nlm.nih.gov/pubmed/25368992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109718
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