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Silymarin Prevents Palmitate-Induced Lipotoxicity in HepG2 Cells: Involvement of Maintenance of Akt Kinase Activation

Whereas adipocytes have a unique capacity to store excess free fatty acids in the form of triglyceride in lipid droplets, non-adipose tissues, such as liver, have a limited capacity for storage of lipids. Saturated long-chain fatty acids, such as palmitate, are the major contributors to lipotoxicity...

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Библиографические подробности
Опубликовано в: :Basic Clin Pharmacol Toxicol
Главные авторы: Song, Zhenyuan, Song, Ming, Lee, David Y. W., Liu, Yanze, Deaciuc, Ion V., McClain, Craig J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219607/
https://ncbi.nlm.nih.gov/pubmed/17845508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-7843.2007.00116.x
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