Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD

BACKGROUND: In models of COPD, environmental stressors induce innate immune responses, inflammasome activation and inflammation. However, the interaction between these responses and their role in driving pulmonary inflammation in stable COPD is unknown. OBJECTIVES: To investigate the activation of i...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Di Stefano, Antonino, Caramori, Gaetano, Barczyk, Adam, Vicari, Chiara, Brun, Paola, Zanini, Andrea, Cappello, Francesco, Garofano, Elvira, Padovani, Anna, Contoli, Marco, Casolari, Paolo, Durham, Andrew L, Chung, Kian Fan, Barnes, Peter J, Papi, Alberto, Adcock, Ian, Balbi, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219154/
https://ncbi.nlm.nih.gov/pubmed/24430176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2012-203062
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